How to Target Your Most Valuable Users in Real Time

For years, marketers have chased personalization, tailoring content by name, industry, or role. Today, that’s just the baseline. To truly move the needle, you need to go beyond basic personalization and target your most valuable audiences with precision.

People’s behaviors—not their job titles—are your most valuable signals. Modern marketers need to activate those signals in real time, across every channel.

In this post, we’ll share three proven strategies for finding and reaching your highest-value audiences—powered by real-time data, behavioral cohorts, and modern experimentation tools like Amplitude.

1. Segment based on what people do, not who they are

Effective targeting starts with understanding what your users do. Modern marketers need a tool to define and activate audiences based on real-time behaviors. Think: users who visited the pricing page multiple times this week but didn’t convert, or those who completed onboarding but haven’t engaged with a key feature.

The right tool should help you create behavioral segments that automatically update as users take (or don’t take) action. These segments should be usable across campaigns—in ads, emails, and web experiments—without needing constant manual updates or CSV exports.

That’s precisely what Amplitude’s behavioral cohorts enable. You can explore, build, and activate cohorts based on user behavior directly from your workflows. These segments update in real time, so your targeting is always relevant, not reactive. For example, you can instantly launch a re-engagement campaign for users who haven’t returned after completing onboarding—without writing a single line of SQL.

Try this: Create a behavioral cohort for users who viewed your pricing twice in the last 48 hours and send it directly to your ad platform or an engagement tool like Braze.

2. Personalize the website experience, not just the message

Most marketers personalize channels—emails, ads, and even SMS. But the website experience is often left untouched, even though it’s where many users decide to bounce or convert. The ideal web experience should serve different on-site content or flows based on user behavior, intent, or lifecycle stage.

One way to get started is targeting web experiments by cohort, showing different calls to action (CTAs) based on prior product usage, or highlighting tailored value propositions based on engagement signals.

With the ability to target by cohort in Amplitude Web Experimentation, you can run website tests based on user behavior, without requiring engineering resources. For example, show a “Book a demo” CTA to trial users who activated a feature or promote a case study to visitors from a specific industry.

Try this: Run an experiment showing a customized pricing page to users who’ve hit a usage limit in your free plan, emphasizing the exact features or capacity they’d unlock by upgrading.

3. Deliver a cohesive, connected experience across channels

Precision targeting doesn’t stop at one channel. You need tools to activate the same behavioral segments across all touchpoints—ads, email, in-app, push—and respond to behavior as it happens.

An ideal system should support real-time cohort syncing with top ad platforms, marketing automation tools, and product messaging platforms. That way, when someone qualifies for a segment (like “Dropped Off Onboarding”), the system automatically updates everywhere—no waiting and no duplication.

With Amplitude’s ad and engagement integrations, you can sync dynamic behavioral cohorts to cross-channel customer engagement platforms or your preferred ad platforms.

Try this: Build a cohort for users who have been in your trial experience for more than seven days but haven’t activated. Then sync it to Braze for a personalized nudge while running Facebook retargeting.

Make precision targeting your competitive advantage

The difference between “good enough” and truly effective marketing often comes down to targeting—not just who you target but when, where, and how you engage. With the right behavioral signals and tools to act in real time, marketers can create experiences that feel intuitive, relevant, and timely.

Whether you’re looking to improve conversion, increase retention, or reduce acquisition costs, behavior-based targeting helps you win faster. Amplitude gives you the real-time insights, dynamic cohorts, and activation tools to identify your most valuable audiences—and reach them across every channel, exactly when it matters.